STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slit_0183TIGRFAM: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; KEGG: dar:Daro_0423 D-alanyl-D-alanine carboxypeptidase PBP3; PFAM: peptidase S13 D-Ala-D-Ala carboxypeptidase C. (494 aa)    
Predicted Functional Partners:
mtgA
Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.
  
  
 0.922
ftsI
Peptidoglycan glycosyltransferase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.
     
 0.917
Slit_0107
KEGG: nmu:Nmul_A2078 penicillin-binding protein 1A; TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase.
     
 0.915
Slit_1177
Manually curated; TIGRFAM: penicillin-binding protein 1C; KEGG: bch:Bcen2424_5133 penicillin-binding protein 1C; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; Penicillin-binding domain protein.
   
 
 0.914
mrdA
Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
     
 0.913
Slit_1228
Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).
     
 0.913
Slit_0726
Beta-lactamase; KEGG: net:Neut_0761 serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; Belongs to the peptidase S11 family.
     
 0.906
Slit_2307
PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; KEGG: gur:Gura_4141 serine-type D-Ala-D-Ala carboxypeptidase; Belongs to the peptidase S11 family.
     
 0.906
Slit_0184
KEGG: nmu:Nmul_A2364 adenosylmethionine-8-amino-7-oxononanoate aminotransferase; TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
       0.813
Slit_1990
PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: nmu:Nmul_A1226 ErfK/YbiS/YcfS/YnhG.
     
 0.567
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.