Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Slit_0253Fibronectin type III domain protein; KEGG: dol:Dole_3024 TPR repeat-containing protein; PFAM: Fibronectin type III domain protein; TPR repeat-containing protein; NHL repeat containing protein; SMART: Tetratricopeptide repeat; Fibronectin type III domain protein. (1251 aa)    
Predicted Functional Partners:
Slit_0252
Adenylate/guanylate cyclase with Chase sensor; KEGG: sat:SYN_01481 adenylate cyclase; PFAM: CHASE2 domain protein; adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase.
 
     0.735
Slit_0254
KEGG: dol:Dole_3025 hypothetical protein.
       0.618
Slit_2622
Carboxyl-terminal protease; SMART: peptidase S41; PDZ/DHR/GLGF domain protein; TIGRFAM: carboxyl-terminal protease; KEGG: mei:Msip34_0439 carboxyl-terminal protease; PFAM: peptidase S41; PDZ/DHR/GLGF domain protein; Belongs to the peptidase S41A family.
   
 
 0.486
Slit_2621
PFAM: Peptidase M23; KEGG: nmu:Nmul_A1120 peptidase M23B.
   
   0.474
Slit_2308
Manually curated; PFAM: Tetratricopeptide TPR_2 repeat protein; KEGG: gur:Gura_1321 TPR repeat-containing protein; SMART: Tetratricopeptide repeat.
 
     0.463
Slit_1026
KEGG: rme:Rmet_2903 hypothetical protein.
   
    0.461
Slit_1027
KEGG: rme:Rmet_2903 hypothetical protein.
   
    0.461
prfA
Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
       0.452
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
       0.446
Slit_0612
KEGG: bac:BamMC406_0165 TPR repeat-containing protein; PFAM: TPR repeat-containing protein; SMART: Tetratricopeptide repeat.
 
     0.441
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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