STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Slit_0259Integral membrane sensor signal transduction histidine kinase; KEGG: mei:Msip34_0036 histidine kinase internal region; PFAM: histidine kinase internal region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein. (343 aa)    
Predicted Functional Partners:
Slit_0260
Two component transcriptional regulator, LytTR family; KEGG: azo:azo0991 alginate biosynthesis regulatory protein AlgR; PFAM: response regulator receiver; LytTr DNA-binding region; SMART: response regulator receiver; LytTr DNA-binding region.
 
 
 0.997
Slit_0585
Multi-sensor hybrid histidine kinase; KEGG: pin:Ping_2140 fused multi-sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-4 domain protein; histidine kinase A domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; PAS domain containing protein; histidine kinase A domain protein; Hpt domain protein.
 
    
 0.896
Slit_2828
Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; histidine kinase A domain protein; KEGG: nmu:Nmul_A1289 multi-sensor signal transduction histidine kinase; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; histidine kinase A domain protein.
 
      0.867
Slit_0261
Two component transcriptional regulator, winged helix family; KEGG: tbd:Tbd_2611 two component transcriptional regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; transcriptional regulator domain protein.
     
 0.776
Slit_0262
KEGG: tbd:Tbd_2610 periplasmic sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein.
     
 0.776
Slit_1761
KEGG: xau:Xaut_0992 integral membrane sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver.
 
    
 0.726
Slit_1160
KEGG: mgm:Mmc1_3164 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein.
 
    
 0.643
argH
KEGG: mei:Msip34_0037 argininosuccinate lyase; TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase.
       0.607
Slit_1463
KEGG: dar:Daro_2339 hypothetical protein.
 
     0.554
Slit_2938
KEGG: dar:Daro_3897 CheW protein; PFAM: CheW domain protein; SMART: CheW domain protein.
  
     0.551
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.