Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Slit_0260Two component transcriptional regulator, LytTR family; KEGG: azo:azo0991 alginate biosynthesis regulatory protein AlgR; PFAM: response regulator receiver; LytTr DNA-binding region; SMART: response regulator receiver; LytTr DNA-binding region. (254 aa)    
Predicted Functional Partners:
Slit_0259
Integral membrane sensor signal transduction histidine kinase; KEGG: mei:Msip34_0036 histidine kinase internal region; PFAM: histidine kinase internal region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein.
 
 
 0.997
Slit_0262
KEGG: tbd:Tbd_2610 periplasmic sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein.
 
   
 0.831
Slit_0261
Two component transcriptional regulator, winged helix family; KEGG: tbd:Tbd_2611 two component transcriptional regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; transcriptional regulator domain protein.
 
   
 0.820
Slit_2940
KEGG: tbd:Tbd_2552 response regulator receiver domain-containing protein; PFAM: response regulator receiver; SMART: response regulator receiver.
  
   
 0.684
Slit_2939
KEGG: app:CAP2UW1_3587 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver.
  
   
 0.634
Slit_2938
KEGG: dar:Daro_3897 CheW protein; PFAM: CheW domain protein; SMART: CheW domain protein.
  
   
 0.613
Slit_1463
KEGG: dar:Daro_2339 hypothetical protein.
  
     0.611
argH
KEGG: mei:Msip34_0037 argininosuccinate lyase; TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase.
       0.607
Slit_2634
KEGG: app:CAP2UW1_0767 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein.
  
     0.591
Slit_2937
KEGG: dar:Daro_3896 chemotaxis sensory transducer; PFAM: chemotaxis sensory transducer; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein.
  
     0.549
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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