Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Slit_0285KEGG: tbd:Tbd_1981 rhodanese-like protein; PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein. (140 aa)    
Predicted Functional Partners:
Slit_1208
KEGG: rfr:Rfer_3913 rhodanese-like protein; PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein.
 
     0.623
Slit_1210
KEGG: rfr:Rfer_3913 rhodanese-like protein; PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein.
 
     0.590
Slit_0284
MltA domain protein; KEGG: tbd:Tbd_2232 membrane-bound lytic murein transglycosylase A; manually curated; PFAM: MltA domain protein; 3D domain protein.
       0.533
apaG
PFAM: ApaG domain protein; KEGG: mei:Msip34_2781 ApaG domain protein.
       0.509
ispF
2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
  
    0.447
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
Server load: low (8%) [HD]