Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_0320PFAM: major facilitator superfamily MFS_1; KEGG: pfs:PFLU6049 putative transport-related membrane protein. (421 aa)    
Predicted Functional Partners:
Slit_0315
PFAM: glycosyl transferase family 9; KEGG: pol:Bpro_0465 glycosyl transferase family protein.
       0.773
Slit_0316
PFAM: GtrA family protein; KEGG: pna:Pnap_0318 GtrA family protein.
       0.773
Slit_0317
PFAM: glycosyl transferase family 39; KEGG: pnu:Pnuc_1247 glycosyl transferase family protein.
       0.773
Slit_0318
KEGG: pst:PSPTO_1897 BNR/Asp-box repeat protein.
       0.773
Slit_0319
KEGG: pna:Pnap_3074 hypothetical protein.
       0.773
Slit_1680
PFAM: Nitrate reductase gamma subunit; KEGG: tbd:Tbd_2479 putative DsrM protein.
  
  
 0.718
cysG
uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
  
  
 0.650
Slit_0321
KEGG: tbd:Tbd_0863 trans-hexaprenyltranstransferase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
       0.547
Slit_0314
Cyclic nucleotide-binding protein; KEGG: azo:azo0988 putative serine/threonine protein kinase; PFAM: Serine/threonine-protein kinase-like domain; cyclic nucleotide-binding; SMART: cyclic nucleotide-binding.
  
  
 0.536
Slit_0160
PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; BFD domain protein [2Fe-2S]-binding domain protein; molybdopterin oxidoreductase Fe4S4 region; KEGG: hch:HCH_05823 anaerobic dehydrogenase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
  
  
 0.526
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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