Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
Slit_0326Peptidase M23; Manually curated; PFAM: Peptidase M23; Peptidoglycan-binding lysin domain; KEGG: app:CAP2UW1_1365 peptidase M23; SMART: Peptidoglycan-binding LysM. (317 aa)    
Predicted Functional Partners:
surE
Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
  
  
 0.825
pcm
protein-L-isoaspartate O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
     
 0.807
Slit_0327
KEGG: net:Neut_1287 radical SAM domain-containing protein.
       0.773
Slit_2450
PFAM: Peptidase M23; KEGG: mei:Msip34_0066 peptidase M23.
  
   
 0.757
Slit_0328
KEGG: hypothetical protein.
       0.705
Slit_0107
KEGG: nmu:Nmul_A2078 penicillin-binding protein 1A; TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase.
  
   
 0.555
Slit_0329
PFAM: Na+/solute symporter; KEGG: rso:RSc0463 sodium/solute symporter transmembrane protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
    0.488
mtgA
Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.
  
     0.482
secD
Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
 
   
 0.481
Slit_1178
N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; KEGG: mfa:Mfla_1381 N-acetylmuramoyl-L-alanine amidase; SMART: cell wall hydrolase/autolysin.
 
   
 0.464
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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