Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_0329PFAM: Na+/solute symporter; KEGG: rso:RSc0463 sodium/solute symporter transmembrane protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (506 aa)    
Predicted Functional Partners:
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
  
 0.658
Slit_0330
Two component transcriptional regulator PhoB, winged helix family; TIGRFAM: phosphate regulon transcriptional regulatory protein PhoB; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: lhk:LHK_00165 PhoB; SMART: response regulator receiver; transcriptional regulator domain protein.
     
 0.561
Slit_0064
PFAM: conserved hypothetical protein; KEGG: dar:Daro_0052 hypothetical protein.
  
     0.528
Slit_0328
KEGG: hypothetical protein.
       0.508
Slit_0326
Peptidase M23; Manually curated; PFAM: Peptidase M23; Peptidoglycan-binding lysin domain; KEGG: app:CAP2UW1_1365 peptidase M23; SMART: Peptidoglycan-binding LysM.
  
    0.488
surE
Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
       0.468
pcm
protein-L-isoaspartate O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
       0.468
Slit_0327
KEGG: net:Neut_1287 radical SAM domain-containing protein.
       0.468
Slit_0712
Exodeoxyribonuclease V; KEGG: tbd:Tbd_0033 DNA helicase/exodeoxyribonuclease V, subunit A; PFAM: UvrD/REP helicase; Belongs to the helicase family. UvrD subfamily.
  
     0.457
Slit_0080
TIGRFAM: urea carboxylase; urea amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; biotin carboxylase domain protein; Carbamoyl-phosphate synthetase large chain domain protein; biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthase L chain ATP-binding; KEGG: nmu:Nmul_A0943 allophanate hydrolase subunit 2; SMART: Allophanate hydrolase subunit 2; biotin carboxylase domain protein; Allophanate hydrolase subunit 1.
  
  
 0.455
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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