Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Slit_0343KEGG: gme:Gmet_2381 transmembrane protein. (547 aa)    
Predicted Functional Partners:
Slit_0344
PFAM: peptidase M48 Ste24p; KEGG: tbd:Tbd_0040 hypothetical protein.
       0.773
Slit_1291
ZipA FtsZ-binding region; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. Belongs to the ZipA family.
  
     0.735
Slit_0288
Manually curated; KEGG: mei:Msip34_1876 hypothetical protein.
  
     0.657
rpmE
Ribosomal protein L31; Binds the 23S rRNA.
       0.619
Slit_0508
PFAM: ribonuclease II; KEGG: net:Neut_0498 ribonuclease II.
  
     0.592
Slit_2058
KEGG: nmu:Nmul_A2067 hypothetical protein.
  
     0.587
Slit_0063
PFAM: protein of unknown function DUF526; KEGG: mms:mma_0167 hypothetical protein.
  
     0.567
Slit_2408
PFAM: permease YjgP/YjgQ family protein; KEGG: mei:Msip34_0237 permease YjgP/YjgQ family protein.
 
     0.543
Slit_0976
PFAM: NUDIX hydrolase; KEGG: neu:NE2253 dATP pyrophosphohydrolase.
  
     0.501
lapB
Tetratricopeptide TPR_2 repeat protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family.
  
     0.488
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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