Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
plsYProtein of unknown function DUF205; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (207 aa)    
Predicted Functional Partners:
plsX
Fatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
 
  
 0.993
gpsA
KEGG: tbd:Tbd_2404 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
 
 0.990
Slit_0471
KEGG: mfa:Mfla_0642 phospholipid/glycerol acyltransferase; PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase.
  
 
 0.936
Slit_2458
PFAM: Carbohydrate kinase, FGGY-like; KEGG: fal:FRAAL4566 glycerol kinase.
    
 0.932
Slit_2464
KEGG: har:HEAR2735 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase.
  
 
 0.921
Slit_2280
PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: aeh:Mlg_2564 NAD-dependent glycerol-3-phosphate dehydrogenase domain-containing protein; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
  
 
 0.917
Slit_2459
PFAM: FAD dependent oxidoreductase; KEGG: saq:Sare_4611 FAD dependent oxidoreductase.
     
 0.915
Slit_0303
KEGG: tgr:Tgr7_0836 protein of unknown function DUF224 cysteine-rich region domain protein.
     
  0.900
Slit_0840
PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: azo:azo0062 hypothetical protein.
     
  0.900
Slit_0346
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
  
    0.648
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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