Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_0350PFAM: Beta-ketoacyl synthase; KEGG: pna:Pnap_1371 3-oxoacyl-(acyl carrier protein) synthase I; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (397 aa)    
Predicted Functional Partners:
Slit_1529
KEGG: mfa:Mfla_1506 [acyl-carrier-protein] S-malonyltransferase; TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase.
 0.999
Slit_0353
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: dar:Daro_4188 3-ketoacyl-(acyl-carrier-protein) reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 0.995
fabH
3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
 0.978
Slit_1799
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: eba:ebA6664 enoyl-[acyl-carrier-protein] reductase.
 
 
 0.971
Slit_0359
PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein; KEGG: rfr:Rfer_3974 3-oxoacyl-(acyl carrier protein) synthase III.
  
 
 0.970
Slit_0356
PFAM: Beta-ketoacyl synthase; KEGG: rfr:Rfer_3977 beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
  
 
0.962
Slit_1530
3-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 0.961
Slit_0354
KEGG: azo:azo0262 hypothetical protein.
 
 
 0.954
Slit_0352
KEGG: bcj:BCAL0836 hypothetical protein.
 
   
 0.948
Slit_0351
KEGG: tbd:Tbd_2754 hypothetical protein.
     0.947
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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