Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Slit_0390KEGG: noc:Noc_0305 hypothetical protein. (88 aa)    
Predicted Functional Partners:
Slit_0389
PFAM: protein of unknown function DUF82; KEGG: pzu:PHZ_c2983 hypothetical protein.
 
     0.808
ruvB
Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
  
    0.713
Slit_0391
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: nmu:Nmul_A0735 short-chain dehydrogenase/reductase SDR.
       0.645
Slit_0388
TIGRFAM: para-aminobenzoate synthase, subunit I; KEGG: mfa:Mfla_1648 aminodeoxychorismate synthase, subunit I; PFAM: Chorismate binding-like; Anthranilate synthase component I domain protein.
       0.631
queA
S-adenosylmethionine/tRNA-ribosyltransferase- isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
  
    0.557
Slit_0387
PFAM: 20S proteasome A and B subunits; KEGG: lhk:LHK_02183 ATP-dependent protease peptidase subunit.
       0.467
Slit_0269
PFAM: protein of unknown function DUF513 hemX; KEGG: nmu:Nmul_A2688 hypothetical protein.
  
  
 0.432
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.