Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Slit_0396KEGG: mea:Mex_1p1858 putative glucoamylase, (glucan 1,4-alpha-glucosidase); PFAM: Glucodextranase N; glycoside hydrolase 15-related. (791 aa)    
Predicted Functional Partners:
glgB
1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
  
 
 0.918
Slit_0980
Glycogen/starch/alpha-glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
   
 
 0.905
Slit_1806
Glycogen/starch/alpha-glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
   
 
 0.905
Slit_1037
TIGRFAM: 4-alpha-glucanotransferase; KEGG: pna:Pnap_1102 4-alpha-glucanotransferase; PFAM: glycoside hydrolase family 77.
    
  0.904
zwf
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
 
     0.823
Slit_0394
6-phosphogluconate dehydrogenase, decarboxylating; KEGG: bbt:BBta_6316 6-phosphogluconate dehydrogenase-like protein; TIGRFAM: 6-phosphogluconate dehydrogenase, decarboxylating; PFAM: 6-phosphogluconate dehydrogenase NAD-binding; 6-phosphogluconate dehydrogenase domain protein.
 
     0.571
glk
TIGRFAM: glucokinase; KEGG: gvi:gll1169 glucokinase; PFAM: Glucokinase; Belongs to the bacterial glucokinase family.
    
 0.554
pgl
6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
 
     0.483
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.