STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hprKHPr kinase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). (311 aa)    
Predicted Functional Partners:
Slit_0104
Phosphotransferase system, phosphocarrier protein HPr; KEGG: mfa:Mfla_0147 HPrNtr; TIGRFAM: phosphocarrier, HPr family; PFAM: phosphoryl transfer system HPr.
 
 
 
 0.871
Slit_0105
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
   
 0.854
Slit_0434
Putative PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: neu:NE0060 phosphotransferase system mannitol/fructose-specific IIA domain-containing protein.
 
   
 0.843
Slit_2486
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding; Pyruvate/ketoisovalerate oxidoreductase; KEGG: hha:Hhal_0066 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein.
   
 
 0.714
Slit_2972
KEGG: gsu:GSU3438 hypothetical protein; TIGRFAM: alkylphosphonate utilization operon protein PhnA; PFAM: PhnA protein.
 
      0.671
Slit_0103
PFAM: PTS system fructose subfamily IIA component; KEGG: mmb:Mmol_2160 PTS system fructose subfamily IIA component.
 
   
 0.603
Slit_0432
Conserved hypothetical protein; Displays ATPase and GTPase activities.
     
 0.582
Slit_0435
KEGG: neu:NE0061 sigma 54 modulation protein / S30EA ribosomal protein; TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA.
     
 0.553
Slit_0436
RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
     
 0.552
lgt
Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.
  
  
 0.547
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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