Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Slit_0442PFAM: sodium/hydrogen exchanger; TrkA-N domain protein; TrkA-C domain protein; KEGG: cvi:CV_3326 glutathione-regulated potassium-efflux system protein; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. (666 aa)    
Predicted Functional Partners:
Slit_0570
KEGG: mmb:Mmol_0945 flagellar basal-body rod protein FlgG; TIGRFAM: flagellar basal-body rod protein FlgG; fagellar hook-basal body protein; PFAM: protein of unknown function DUF1078 domain protein; flagellar basal body rod protein; Belongs to the flagella basal body rod proteins family.
    
   0.805
Slit_0436
RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
     
 0.741
Slit_0441
KpsF/GutQ family protein; SMART: CBS domain containing protein; TIGRFAM: KpsF/GutQ family protein; KEGG: app:CAP2UW1_0637 KpsF/GutQ family protein; PFAM: sugar isomerase (SIS); CBS domain containing protein; Belongs to the SIS family. GutQ/KpsF subfamily.
     
 0.668
Slit_0437
KEGG: app:CAP2UW1_4310 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase.
       0.649
lptA
Lipopolysaccharide transport periplasmic protein LptA; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane.
       0.649
Slit_0439
PFAM: protein of unknown function DUF1239; KEGG: mfa:Mfla_0139 hypothetical protein.
       0.649
Slit_0440
KEGG: tbd:Tbd_0537 phosphatase KdsC; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; hydrolase, HAD-superfamily, subfamily IIIA.
       0.649
Slit_0435
KEGG: neu:NE0061 sigma 54 modulation protein / S30EA ribosomal protein; TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA.
  
    0.601
Slit_2943
PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; KEGG: net:Neut_1050 redoxin domain-containing protein.
 
    0.599
Slit_0434
Putative PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: neu:NE0060 phosphotransferase system mannitol/fructose-specific IIA domain-containing protein.
 
     0.541
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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