Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
Slit_0452PFAM: Patatin; KEGG: nmu:Nmul_A2472 patatin. (397 aa)    
Predicted Functional Partners:
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
       0.825
Slit_0451
KEGG: tbd:Tbd_0890 hypothetical protein.
       0.813
Slit_0450
Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+))., Phosphate acetyltransferase; KEGG: azo:azo3211 malic enzyme; PFAM: malic protein NAD-binding; malic protein domain protein; phosphate acetyl/butaryl transferase.
       0.782
coaX
Transcriptional activator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
       0.773
Slit_0455
PFAM: Sporulation domain protein; KEGG: har:HEAR2989 hypothetical protein.
       0.773
Slit_1396
TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; ComEC/Rec2-related protein; PFAM: ComEC/Rec2-related protein; KEGG: nmu:Nmul_A2506 DNA internalization-related competence protein ComEC/Rec2; SMART: beta-lactamase domain protein.
     
 0.514
Slit_0449
PFAM: alpha/beta hydrolase fold; KEGG: bgl:bglu_2g14160 alpha/beta hydrolase fold protein.
       0.467
Slit_1861
PFAM: Protein of unknown function DUF1974; acyl-CoA dehydrogenase domain protein; KEGG: nmu:Nmul_A0094 acyl-CoA dehydrogenase.
 
   
 0.427
Slit_2076
PFAM: Uncharacterised conserved protein UCP015557; KEGG: app:CAP2UW1_1557 hypothetical protein.
  
     0.412
Slit_1166
PFAM: alpha/beta hydrolase fold; KEGG: mpt:Mpe_A0052 hydrolase or acyltransferase-like protein.
 
   
 0.408
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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