close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slit_0477Putative signal transduction protein; PFAM: Metal-dependent hydrolase HDOD; KEGG: app:CAP2UW1_1034 putative signal transduction protein. (290 aa)    
Predicted Functional Partners:
Slit_0728
Putative signal transduction protein; PFAM: Metal-dependent hydrolase HDOD; KEGG: pmy:Pmen_4398 putative signal transduction protein.
  
     0.775
Slit_0478
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; GGDEF domain containing protein; PAS fold-3 domain protein; KEGG: dar:Daro_3990 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein.
   
   0.516
Slit_1202
KEGG: mms:mma_1961 hypothetical protein; PFAM: response regulator receiver; SMART: response regulator receiver; Tetratricopeptide repeat.
  
 
   0.516
Slit_1301
KEGG: dar:Daro_0970 response regulator receiver; PFAM: response regulator receiver; metal-dependent phosphohydrolase HD sub domain; SMART: response regulator receiver; metal-dependent phosphohydrolase HD region.
  
     0.514
Slit_2087
PFAM: Neisseria PilC domain protein; KEGG: mms:mma_3355 type IV fimbrial biogenesis protein PilY1.
  
    0.502
flgI
Flagellar P-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
 
     0.501
Slit_1376
Putative signal transduction protein; PFAM: Metal-dependent hydrolase HDOD; KEGG: mei:Msip34_2001 metal-dependent hydrolase HDOD.
  
     0.471
Slit_2595
KEGG: har:HEAR1941 putative mannose-sensitive agglutinin (MSHA) biogenesis protein MshJ (pilus type IV); putative signal peptide.
  
     0.444
Slit_1590
KEGG: two-component system sensor histidine kinase/response regulator, putative; PFAM: response regulator receiver; SMART: response regulator receiver.
  
     0.425
cheD
CheD; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.
 
     0.423
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
Server load: medium (78%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.