Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
Slit_0510PFAM: cytochrome c class I; KEGG: dar:Daro_3321 cytochrome c, class I. (103 aa)    
Predicted Functional Partners:
Slit_2498
PFAM: cytochrome c class I; KEGG: dar:Daro_1401 cytochrome c, class I.
  
     0.749
Slit_1122
Nitric-oxide reductase; KEGG: dar:Daro_3191 cytochrome c oxidase, subunit I; PFAM: cytochrome c oxidase subunit I; Belongs to the heme-copper respiratory oxidase family.
   
  
 0.733
Slit_0643
PFAM: Polysulphide reductase NrfD; KEGG: gme:Gmet_1812 polysulphide reductase, NrfD.
     
 0.618
Slit_1675
PFAM: Polysulphide reductase NrfD; KEGG: vok:COSY_0784 intracellular sulfur oxidation protein DsrP.
     
 0.618
ntrC
Nitrogen metabolism transcriptional regulator, NtrC, Fis Family; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.
      
 0.618
Slit_0511
PFAM: protein of unknown function DUF28; KEGG: nmu:Nmul_A2722 hypothetical protein.
       0.524
ruvC
Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
       0.436
Slit_0513
PFAM: UbiA prenyltransferase; KEGG: pna:Pnap_1242 UbiA prenyltransferase.
       0.433
Slit_0342
PFAM: glycosyl transferase family 39; KEGG: dfe:Dfer_1293 glycosyl transferase family 39.
  
     0.429
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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