Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
tolQProtein TolQ; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. (225 aa)    
Predicted Functional Partners:
Slit_0518
Protein TolR; Manually curated; TIGRFAM: protein TolR; KEGG: nmu:Nmul_A2716 biopolymer transport protein ExbD/TolR; PFAM: Biopolymer transport protein ExbD/TolR.
 
 
 0.974
tolB
Tol-Pal system beta propeller repeat protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
 
  
 0.937
Slit_1390
PFAM: Biopolymer transport protein ExbD/TolR; KEGG: rme:Rmet_2279 biopolymer transport protein ExbD/TolR.
 
 
 0.928
pal
Peptidoglycan-associated lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
 
   
 0.887
Slit_0519
TIGRFAM: protein TolA; KEGG: neu:NE0217 hypothetical protein.
  
 
 0.849
Slit_0516
KEGG: nmu:Nmul_A2718 4-hydroxybenzoyl-CoA thioesterase; TIGRFAM: tol-pal system-associated acyl-CoA thioesterase; PFAM: thioesterase superfamily protein.
  
  
 0.848
Slit_1365
PFAM: Biopolymer transport protein ExbD/TolR; KEGG: nmu:Nmul_A1028 biopolymer transport protein ExbD/TolR.
 
 
 0.837
cpoB
Tol-pal system protein YbgF; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family.
 
  
 0.815
ruvB
Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
       0.813
Slit_0921
PFAM: OmpA/MotB domain protein; KEGG: dar:Daro_0695 OmpA/MotB.
 
   
 0.778
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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