Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_0530PFAM: Serine/threonine-protein kinase-like domain; CHASE2 domain protein; KEGG: rfr:Rfer_3942 serine/threonine protein kinase with CHASE2 sensor. (843 aa)    
Predicted Functional Partners:
Slit_0531
PFAM: Protein phosphatase 2C-like; KEGG: dar:Daro_3360 protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein.
 
 
 0.938
Slit_0532
FHA domain containing protein; KEGG: dar:Daro_3359 forkhead-associated; PFAM: Forkhead-associated protein; SMART: Forkhead-associated protein.
 
 
 
 0.927
Slit_0402
PFAM: Protein phosphatase 2C-like; KEGG: har:HEAR2127 putative serine/threonine specific protein phosphatase; SMART: protein phosphatase 2C domain protein.
 
 
 0.823
Slit_0534
SMART: beta-lactamase domain protein; KEGG: app:CAP2UW1_0661 beta-lactamase domain protein.
 
    0.681
Slit_0050
KEGG: app:CAP2UW1_3892 adenylate/guanylate cyclase; PFAM: Forkhead-associated protein; adenylyl cyclase class-3/4/guanylyl cyclase; SMART: Forkhead-associated protein; adenylyl cyclase class-3/4/guanylyl cyclase.
 
 
 
 0.672
Slit_0537
Metal dependent phosphohydrolase; KEGG: dar:Daro_3357 hypothetical protein; PFAM: GAF domain protein; metal-dependent phosphohydrolase HD sub domain; SMART: GAF domain protein; metal-dependent phosphohydrolase HD region.
 
   
 0.657
Slit_1432
Putative transcriptional regulator, Crp/Fnr family; KEGG: dal:Dalk_2479 cyclic nucleotide-binding protein; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding.
 
   
 0.582
Slit_0529
PFAM: UspA domain protein; KEGG: neu:NE2292 universal stress protein.
     
 0.554
Slit_0679
KEGG: app:CAP2UW1_0632 hypothetical protein.
  
     0.529
Slit_0528
PFAM: Integral membrane protein TerC; KEGG: app:CAP2UW1_3848 integral membrane protein TerC.
  
    0.528
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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