STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slit_0535Putative transcriptional regulator, Crp/Fnr family; KEGG: mmb:Mmol_0609 cyclic nucleotide-binding protein; PFAM: cyclic nucleotide-binding; Rhodanese domain protein; SMART: cyclic nucleotide-binding; Rhodanese domain protein. (358 aa)    
Predicted Functional Partners:
Slit_0533
KEGG: mfa:Mfla_2129 adenylate/guanylate cyclase; PFAM: CHASE2 domain protein; adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase.
 
 0.766
rpoH
RNA polymerase, sigma 32 subunit, RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.
   
 
 0.764
rpoD
RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
 
 0.761
Slit_0534
SMART: beta-lactamase domain protein; KEGG: app:CAP2UW1_0661 beta-lactamase domain protein.
     
 0.726
Slit_2198
KEGG: app:CAP2UW1_3892 adenylate/guanylate cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; Ankyrin; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; Ankyrin.
 
 0.703
Slit_0536
KEGG: net:Neut_2128 putative GAF sensor protein; PFAM: type II secretion system protein E; General secretory system II protein E domain protein; GAF domain protein; SMART: GAF domain protein; AAA ATPase.
     
 0.698
Slit_0537
Metal dependent phosphohydrolase; KEGG: dar:Daro_3357 hypothetical protein; PFAM: GAF domain protein; metal-dependent phosphohydrolase HD sub domain; SMART: GAF domain protein; metal-dependent phosphohydrolase HD region.
   
 
 0.684
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
   0.666
Slit_2800
Putative transcriptional regulator, Crp/Fnr family; KEGG: hypothetical protein; K04739 cAMP-dependent protein kinase regulator; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding.
  
    0.665
Slit_0050
KEGG: app:CAP2UW1_3892 adenylate/guanylate cyclase; PFAM: Forkhead-associated protein; adenylyl cyclase class-3/4/guanylyl cyclase; SMART: Forkhead-associated protein; adenylyl cyclase class-3/4/guanylyl cyclase.
 
 0.645
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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