STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slit_0537Metal dependent phosphohydrolase; KEGG: dar:Daro_3357 hypothetical protein; PFAM: GAF domain protein; metal-dependent phosphohydrolase HD sub domain; SMART: GAF domain protein; metal-dependent phosphohydrolase HD region. (544 aa)    
Predicted Functional Partners:
Slit_0534
SMART: beta-lactamase domain protein; KEGG: app:CAP2UW1_0661 beta-lactamase domain protein.
     0.976
Slit_0878
SMART: beta-lactamase domain protein; KEGG: net:Neut_2129 cyclic-AMP phosphodiesterase.
     0.927
Slit_0533
KEGG: mfa:Mfla_2129 adenylate/guanylate cyclase; PFAM: CHASE2 domain protein; adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase.
 
 
 
 0.903
Slit_0536
KEGG: net:Neut_2128 putative GAF sensor protein; PFAM: type II secretion system protein E; General secretory system II protein E domain protein; GAF domain protein; SMART: GAF domain protein; AAA ATPase.
     
 0.785
Slit_0252
Adenylate/guanylate cyclase with Chase sensor; KEGG: sat:SYN_01481 adenylate cyclase; PFAM: CHASE2 domain protein; adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase.
 
 
 
 0.768
Slit_2048
KEGG: sse:Ssed_3621 putative adenylate/guanylate cyclase; PFAM: CHASE2 domain protein; adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase.
 
 
 
 0.767
Slit_2043
KEGG: mfa:Mfla_1127 hypothetical protein.
 
     0.761
Slit_2211
KEGG: mfa:Mfla_1127 hypothetical protein.
 
     0.744
Slit_1160
KEGG: mgm:Mmc1_3164 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein.
  
 
 0.707
Slit_2311
PFAM: CHASE2 domain protein; KEGG: mei:Msip34_1734 putative CHASE2 sensor protein.
 
     0.686
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.