STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
flhDFlagellar transcriptional activator; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhD family. (106 aa)    
Predicted Functional Partners:
flhC
Flagellar transcriptional activator FlhC; Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhC family.
 
 
 0.999
Slit_0543
PFAM: OmpA/MotB domain protein; KEGG: mms:mma_2098 flagellar motor protein MotB.
 
  
 0.890
Slit_2486
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding; Pyruvate/ketoisovalerate oxidoreductase; KEGG: hha:Hhal_0066 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein.
    
   0.855
Slit_0542
PFAM: MotA/TolQ/ExbB proton channel; KEGG: tbd:Tbd_1243 flagellar motor protein MotA.
 
    0.823
Slit_0594
KEGG: dar:Daro_0769 flagellar biosynthesis chaperone FliJ-like protein; TIGRFAM: flagellar export protein FliJ; PFAM: flagellar FliJ protein.
  
   
 0.724
Slit_2143
PFAM: major facilitator superfamily MFS_1; KEGG: tbd:Tbd_1718 lysophospholipid transporter LplT.
  
     0.690
Slit_0550
Chemotaxis phosphatase, CheZ; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).
 
  
 0.687
Slit_0592
Flagellar basal body-associated protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.
  
   
 0.668
Slit_0462
PFAM: major facilitator superfamily MFS_1; KEGG: mei:Msip34_2774 major facilitator superfamily MFS_1.
  
     0.663
Slit_0737
Transcriptional regulator, TetR family; PFAM: regulatory protein TetR; KEGG: dar:Daro_0627 nucleoid occlusion protein.
  
     0.606
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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