Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_0543PFAM: OmpA/MotB domain protein; KEGG: mms:mma_2098 flagellar motor protein MotB. (341 aa)    
Predicted Functional Partners:
Slit_0542
PFAM: MotA/TolQ/ExbB proton channel; KEGG: tbd:Tbd_1243 flagellar motor protein MotA.
 0.999
Slit_0560
PFAM: MotA/TolQ/ExbB proton channel; KEGG: azo:azo1108 flagellar motor protein.
  
 0.991
flhC
Flagellar transcriptional activator FlhC; Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhC family.
  
 0.987
Slit_0574
KEGG: nmu:Nmul_A1330 flagellar hook-associated protein FlgK; TIGRFAM: flagellar hook-associated protein FlgK; PFAM: protein of unknown function DUF1078 domain protein; flagellar basal body rod protein; Belongs to the flagella basal body rod proteins family.
 
  
 0.962
Slit_0550
Chemotaxis phosphatase, CheZ; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).
 
  
 0.950
Slit_0547
KEGG: app:CAP2UW1_3839 response regulator receiver modulated CheW protein; PFAM: CheW domain protein; response regulator receiver; SMART: CheW domain protein; response regulator receiver.
  
  
 0.936
fliA
RNA polymerase, sigma 28 subunit, FliA/WhiG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.
 
  
 0.934
Slit_0561
PFAM: OmpA/MotB domain protein; KEGG: nmu:Nmul_A1315 flagellar motor protein MotD.
    
0.918
Slit_0551
CheA signal transduction histidine kinase; KEGG: azo:azo1462 chemotaxis protein CheA; PFAM: ATP-binding region ATPase domain protein; CheW domain protein; Hpt domain protein; Signal transducing histidine kinase homodimeric; SMART: ATP-binding region ATPase domain protein; CheW domain protein; Hpt domain protein.
 
  
 0.908
Slit_0598
Flagellar M-ring protein FliF; The M ring may be actively involved in energy transduction. Belongs to the FliF family.
 
  
 0.908
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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