Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_0580Methyltransferase type 12; KEGG: cvi:CV_1368 hypothetical protein; PFAM: Methyltransferase type 12; TPR repeat-containing protein; SMART: Tetratricopeptide repeat. (436 aa)    
Predicted Functional Partners:
Slit_0579
PFAM: Protein of unknown function DUF2252; KEGG: bxe:Bxe_B2085 hypothetical protein.
       0.675
Slit_0578
KEGG: ttr:Tter_2251 ABC transporter related protein; PFAM: ABC transporter related; SMART: AAA ATPase.
       0.496
Slit_0577
PFAM: ABC-2 type transporter; KEGG: cpc:Cpar_1860 ABC-2 type transporter.
       0.492
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
    0.469
Slit_0253
Fibronectin type III domain protein; KEGG: dol:Dole_3024 TPR repeat-containing protein; PFAM: Fibronectin type III domain protein; TPR repeat-containing protein; NHL repeat containing protein; SMART: Tetratricopeptide repeat; Fibronectin type III domain protein.
 
     0.430
Slit_0602
Methyltransferase type 12; KEGG: dat:HRM2_00990 two domain fusion protein (N:methyltransferase, C:TPR-repeat family protein); PFAM: Methyltransferase type 12; TPR repeat-containing protein; Methyltransferase type 11; SMART: Tetratricopeptide repeat; MCP methyltransferase CheR-type.
 
   
0.427
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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