Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_0612KEGG: bac:BamMC406_0165 TPR repeat-containing protein; PFAM: TPR repeat-containing protein; SMART: Tetratricopeptide repeat. (834 aa)    
Predicted Functional Partners:
Slit_0611
KEGG: bph:Bphy_2998 TPR domain-containing protein.
      0.939
Slit_2622
Carboxyl-terminal protease; SMART: peptidase S41; PDZ/DHR/GLGF domain protein; TIGRFAM: carboxyl-terminal protease; KEGG: mei:Msip34_0439 carboxyl-terminal protease; PFAM: peptidase S41; PDZ/DHR/GLGF domain protein; Belongs to the peptidase S41A family.
  
 
 0.845
Slit_0615
KEGG: neu:NE2077 hypothetical protein.
 
     0.680
Slit_0617
KEGG: mms:mma_1447 FliS flagellar protein; TIGRFAM: flagellar protein FliS; PFAM: flagellar protein FliS.
   
   0.670
Slit_0618
Flagellar hook-associated 2 domain protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
       0.658
ycgR
YcgR family protein; Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility.
       0.620
Slit_0614
PFAM: type III secretion exporter; KEGG: app:CAP2UW1_0921 putative flagellar biosynthetic protein.
       0.616
Slit_0619
PFAM: flagellar protein FlaG protein; KEGG: tbd:Tbd_1591 putative flagellar protein FlaG.
       0.594
Slit_0616
PFAM: flagellar export chaperone; KEGG: har:HEAR1870 putative flagellar synthesis (flagellar regulon).
       0.592
Slit_0686
PFAM: Tetratricopeptide TPR_2 repeat protein; TPR repeat-containing protein; KEGG: app:CAP2UW1_0625 tetratricopeptide TPR_2 repeat protein.
 
 
 0.589
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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