STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ycgRYcgR family protein; Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility. (255 aa)    
Predicted Functional Partners:
Slit_0615
KEGG: neu:NE2077 hypothetical protein.
 
    0.939
Slit_0617
KEGG: mms:mma_1447 FliS flagellar protein; TIGRFAM: flagellar protein FliS; PFAM: flagellar protein FliS.
  
  
 0.892
Slit_0618
Flagellar hook-associated 2 domain protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
  
  
 0.889
Slit_0614
PFAM: type III secretion exporter; KEGG: app:CAP2UW1_0921 putative flagellar biosynthetic protein.
 
  
 0.869
Slit_0619
PFAM: flagellar protein FlaG protein; KEGG: tbd:Tbd_1591 putative flagellar protein FlaG.
 
    0.824
Slit_0550
Chemotaxis phosphatase, CheZ; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).
 
    0.790
Slit_0616
PFAM: flagellar export chaperone; KEGG: har:HEAR1870 putative flagellar synthesis (flagellar regulon).
  
    0.776
Slit_0547
KEGG: app:CAP2UW1_3839 response regulator receiver modulated CheW protein; PFAM: CheW domain protein; response regulator receiver; SMART: CheW domain protein; response regulator receiver.
 
  
 0.764
Slit_0620
Flagellin domain protein; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
  
  
 0.706
Slit_1016
KEGG: tbd:Tbd_1242 hypothetical protein.
  
     0.681
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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