Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Slit_0623PAS/PAC sensor signal transduction histidine kinase; SMART: ATP-binding region ATPase domain protein; manually curated; KEGG: mms:mma_1453 two-component sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; PAS fold-3 domain protein. (395 aa)    
Predicted Functional Partners:
Slit_0622
KEGG: har:HEAR1863 LuxR family transcriptional regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR.
   0.957
Slit_2500
Two component transcriptional regulator, LuxR family; KEGG: rsk:RSKD131_3304 two-component response regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR.
   0.864
Slit_1593
KEGG: bph:Bphy_6558 two component LuxR family transcriptional regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR.
   0.857
Slit_1821
KEGG: sfu:Sfum_1664 two component LuxR family transcriptional regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR.
   0.850
Slit_2581
Two component transcriptional regulator, LuxR family; KEGG: mag:amb3889 response regulator; PFAM: regulatory protein LuxR; response regulator receiver; SMART: regulatory protein LuxR; response regulator receiver.
   0.837
Slit_1727
KEGG: tbd:Tbd_2464 two component LuxR family transcriptional regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR.
   0.836
Slit_0553
MCP methyltransferase, CheR-type; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.
 
      0.832
Slit_2214
KEGG: pol:Bpro_0709 two component LuxR family transcriptional regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR.
 
   0.830
Slit_0151
Two component transcriptional regulator, LuxR family; KEGG: mpt:Mpe_A3237 response regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR.
 
   0.828
Slit_1163
KEGG: mag:amb1840 response regulator; PFAM: response regulator receiver; SMART: response regulator receiver.
 
      0.765
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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