node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Slit_0631 | hisA | Slit_0631 | Slit_0627 | PFAM: histidine triad (HIT) protein; KEGG: nmu:Nmul_A0811 histidine triad (HIT) protein. | KEGG: mei:Msip34_0271 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein. | 0.551 |
Slit_0631 | hisB | Slit_0631 | Slit_0625 | PFAM: histidine triad (HIT) protein; KEGG: nmu:Nmul_A0811 histidine triad (HIT) protein. | KEGG: mmb:Mmol_0314 imidazoleglycerol-phosphate dehydratase; PFAM: imidazoleglycerol-phosphate dehydratase. | 0.520 |
Slit_0631 | hisC | Slit_0631 | Slit_0624 | PFAM: histidine triad (HIT) protein; KEGG: nmu:Nmul_A0811 histidine triad (HIT) protein. | KEGG: nmu:Nmul_A0818 histidinol-phosphate aminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.514 |
Slit_0631 | hisE | Slit_0631 | Slit_0630 | PFAM: histidine triad (HIT) protein; KEGG: nmu:Nmul_A0811 histidine triad (HIT) protein. | KEGG: tbd:Tbd_1706 phosphoribosyl-ATP pyrophosphatase; TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-ATP pyrophosphohydrolase. | 0.806 |
Slit_0631 | hisF | Slit_0631 | Slit_0628 | PFAM: histidine triad (HIT) protein; KEGG: nmu:Nmul_A0811 histidine triad (HIT) protein. | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.551 |
Slit_0631 | hisH | Slit_0631 | Slit_0626 | PFAM: histidine triad (HIT) protein; KEGG: nmu:Nmul_A0811 histidine triad (HIT) protein. | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.560 |
Slit_0631 | hisI | Slit_0631 | Slit_0629 | PFAM: histidine triad (HIT) protein; KEGG: nmu:Nmul_A0811 histidine triad (HIT) protein. | Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | 0.806 |
Slit_0631 | tatA | Slit_0631 | Slit_0632 | PFAM: histidine triad (HIT) protein; KEGG: nmu:Nmul_A0811 histidine triad (HIT) protein. | Twin-arginine translocation protein, TatA/E family subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.768 |
Slit_0631 | tatB | Slit_0631 | Slit_0633 | PFAM: histidine triad (HIT) protein; KEGG: nmu:Nmul_A0811 histidine triad (HIT) protein. | Twin-arginine translocation protein, TatB subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. | 0.760 |
Slit_0631 | tatC | Slit_0631 | Slit_0634 | PFAM: histidine triad (HIT) protein; KEGG: nmu:Nmul_A0811 histidine triad (HIT) protein. | Sec-independent protein translocase, TatC subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. | 0.693 |
hisA | Slit_0631 | Slit_0627 | Slit_0631 | KEGG: mei:Msip34_0271 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein. | PFAM: histidine triad (HIT) protein; KEGG: nmu:Nmul_A0811 histidine triad (HIT) protein. | 0.551 |
hisA | hisB | Slit_0627 | Slit_0625 | KEGG: mei:Msip34_0271 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein. | KEGG: mmb:Mmol_0314 imidazoleglycerol-phosphate dehydratase; PFAM: imidazoleglycerol-phosphate dehydratase. | 0.998 |
hisA | hisC | Slit_0627 | Slit_0624 | KEGG: mei:Msip34_0271 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein. | KEGG: nmu:Nmul_A0818 histidinol-phosphate aminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.968 |
hisA | hisE | Slit_0627 | Slit_0630 | KEGG: mei:Msip34_0271 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein. | KEGG: tbd:Tbd_1706 phosphoribosyl-ATP pyrophosphatase; TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-ATP pyrophosphohydrolase. | 0.989 |
hisA | hisF | Slit_0627 | Slit_0628 | KEGG: mei:Msip34_0271 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein. | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.999 |
hisA | hisH | Slit_0627 | Slit_0626 | KEGG: mei:Msip34_0271 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein. | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.999 |
hisA | hisI | Slit_0627 | Slit_0629 | KEGG: mei:Msip34_0271 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein. | Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | 0.999 |
hisA | tatA | Slit_0627 | Slit_0632 | KEGG: mei:Msip34_0271 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein. | Twin-arginine translocation protein, TatA/E family subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.496 |
hisA | tatB | Slit_0627 | Slit_0633 | KEGG: mei:Msip34_0271 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein. | Twin-arginine translocation protein, TatB subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. | 0.525 |
hisA | tatC | Slit_0627 | Slit_0634 | KEGG: mei:Msip34_0271 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein. | Sec-independent protein translocase, TatC subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. | 0.494 |