Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_0672KEGG: dar:Daro_0918 TPR repeat-containing protein; PFAM: TPR repeat-containing protein; SMART: Tetratricopeptide repeat. (345 aa)    
Predicted Functional Partners:
Slit_0671
PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: dar:Daro_0917 ErfK/YbiS/YcfS/YnhG.
 
     0.950
Slit_0534
SMART: beta-lactamase domain protein; KEGG: app:CAP2UW1_0661 beta-lactamase domain protein.
  
 
   0.587
Slit_0670
Peptidyl-prolyl cis-trans isomerase cyclophilin type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
       0.567
cysS
SMART: Cysteinyl-tRNA synthetase class Ia DALR; TIGRFAM: cysteinyl-tRNA synthetase; KEGG: tmz:Tmz1t_3046 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Cysteinyl-tRNA synthetase class Ia DALR; Belongs to the class-I aminoacyl-tRNA synthetase family.
       0.567
Slit_0532
FHA domain containing protein; KEGG: dar:Daro_3359 forkhead-associated; PFAM: Forkhead-associated protein; SMART: Forkhead-associated protein.
 
    0.560
Slit_0878
SMART: beta-lactamase domain protein; KEGG: net:Neut_2129 cyclic-AMP phosphodiesterase.
  
 
   0.526
glnS
KEGG: lhk:LHK_01404 Syq; TIGRFAM: glutaminyl-tRNA synthetase; PFAM: Glutamyl/glutaminyl-tRNA synthetase, class Ic, catalytic domain; Glutamyl/glutaminyl-tRNA synthetase, class Ic, anti-codon binding domain.
       0.523
Slit_0674
KEGG: tbd:Tbd_1218 transmembrane protein.
       0.523
Slit_1233
PFAM: 17 kDa surface antigen; KEGG: har:HEAR2232 putative signal peptide.
  
     0.516
lpxH
UDP-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
       0.513
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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