STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slit_0689Two component, sigma54 specific, transcriptional regulator, Fis family; Manually curated; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; KEGG: mfa:Mfla_0074 two component, sigma54 specific, fis family transcriptional regulator; SMART: response regulator receiver; AAA ATPase. (471 aa)    
Predicted Functional Partners:
Slit_0688
KEGG: app:CAP2UW1_0623 sporulation domain protein; PFAM: Sporulation domain protein; SMART: AAA ATPase.
 
     0.813
Slit_0436
RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
   
 0.784
Slit_0686
PFAM: Tetratricopeptide TPR_2 repeat protein; TPR repeat-containing protein; KEGG: app:CAP2UW1_0625 tetratricopeptide TPR_2 repeat protein.
 
 
   0.609
Slit_0687
KEGG: dar:Daro_3405 type II and III secretion system protein; TIGRFAM: pilus (MSHA type) biogenesis protein MshL; PFAM: type II and III secretion system protein; Belongs to the bacterial secretin family.
 
     0.608
Slit_0679
KEGG: app:CAP2UW1_0632 hypothetical protein.
 
     0.592
Slit_1160
KEGG: mgm:Mmc1_3164 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein.
  
 
 0.568
Slit_0681
KEGG: dar:Daro_3411 hypothetical protein.
       0.535
Slit_0682
KEGG: mei:Msip34_0084 hypothetical protein.
       0.535
Slit_0683
KEGG: mfa:Mfla_0080 hypothetical protein.
       0.535
Slit_0684
PFAM: Type II secretion system F domain; KEGG: dar:Daro_3408 type II secretion system protein.
       0.535
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.