Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_0711KEGG: har:HEAR0707 hypothetical protein. (869 aa)    
Predicted Functional Partners:
Slit_0712
Exodeoxyribonuclease V; KEGG: tbd:Tbd_0033 DNA helicase/exodeoxyribonuclease V, subunit A; PFAM: UvrD/REP helicase; Belongs to the helicase family. UvrD subfamily.
 
   
 0.936
Slit_0710
4Fe-4S ferredoxin iron-sulfur binding domain protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
       0.810
Slit_0709
PFAM: glutamine amidotransferase class-I; KEGG: mmb:Mmol_0599 glutamine amidotransferase class-I.
       0.723
Slit_2165
TIGRFAM: type IV pilus modification protein PilV; KEGG: rso:RSc2678 type 4 fimbrial biogenesis related transmembrane protein.
  
     0.570
htpG
ATP-binding region ATPase domain protein; Molecular chaperone. Has ATPase activity.
       0.541
xseB
Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.
     
 0.535
Slit_1695
PFAM: protein of unknown function DUF395 YeeE/YedE; KEGG: dar:Daro_4041 YeeE/YedE.
 
     0.485
Slit_2162
Tfp pilus assembly protein tip-associated adhesin PilY1-like protein; KEGG: rpi:Rpic_2911 putative type 4 fimbrial biogenesis PilY1-related protein signal peptide.
  
     0.449
rep
UvrD/REP helicase; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.
   
   0.420
Slit_2844
PFAM: UvrD/REP helicase; KEGG: nmu:Nmul_A0563 UvrD/REP helicase.
   
   0.420
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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