Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Slit_0721PFAM: ABC-2 type transporter; KEGG: cps:CPS_1067 putative ABC transporter, permease protein. (335 aa)    
Predicted Functional Partners:
Slit_0722
KEGG: asa:ASA_1248 ABC-type transporter, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase.
 
  
 0.962
Slit_2512
KEGG: sfu:Sfum_2391 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase.
 
  
 0.743
lipB
Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
       0.697
Slit_0578
KEGG: ttr:Tter_2251 ABC transporter related protein; PFAM: ABC transporter related; SMART: AAA ATPase.
 
  
 0.589
Slit_1251
PFAM: nitroreductase; KEGG: bur:Bcep18194_B1060 hypothetical protein.
  
  
 0.536
Slit_0724
PFAM: protein of unknown function DUF493; KEGG: net:Neut_0759 hypothetical protein; Belongs to the UPF0250 family.
       0.507
Slit_0725
PFAM: aminotransferase class IV; KEGG: nmu:Nmul_A1990 aminotransferase, class IV.
       0.507
Slit_0726
Beta-lactamase; KEGG: net:Neut_0761 serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; Belongs to the peptidase S11 family.
       0.504
Slit_2359
KEGG: mfa:Mfla_0682 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase.
 
  
 0.495
Slit_2511
Efflux transporter, RND family, MFP subunit; KEGG: sfu:Sfum_2390 secretion protein HlyD family protein; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
  
 0.446
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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