Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_0728Putative signal transduction protein; PFAM: Metal-dependent hydrolase HDOD; KEGG: pmy:Pmen_4398 putative signal transduction protein. (287 aa)    
Predicted Functional Partners:
Slit_0477
Putative signal transduction protein; PFAM: Metal-dependent hydrolase HDOD; KEGG: app:CAP2UW1_1034 putative signal transduction protein.
  
     0.775
Slit_0730
KEGG: nmu:Nmul_A0008 periplasmic sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein.
 
 
   0.604
Slit_0729
KEGG: mei:Msip34_0534 two component transcriptional regulator, fis family; PFAM: response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver.
       0.535
Slit_1376
Putative signal transduction protein; PFAM: Metal-dependent hydrolase HDOD; KEGG: mei:Msip34_2001 metal-dependent hydrolase HDOD.
  
     0.433
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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