Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_0742Ribonuclease BN; KEGG: nmu:Nmul_A0452 ribonuclease BN, putative; TIGRFAM: ribonuclease BN; PFAM: ribonuclease BN. (415 aa)    
Predicted Functional Partners:
Slit_1657
TIGRFAM: GTP-binding protein TypA; small GTP-binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain protein; KEGG: tbd:Tbd_0772 GTP-binding protein TypA; SMART: elongation factor G domain protein.
      0.610
Slit_0744
PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; KEGG: mei:Msip34_2316 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen.
       0.575
Slit_0741
PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; KEGG: mei:Msip34_0989 pyridoxamine 5'-phosphate oxidase-related FMN-binding.
       0.565
Slit_0743
PFAM: conserved hypothetical protein; KEGG: mei:Msip34_2317 hypothetical protein.
       0.554
Slit_0060
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.476
Slit_2526
PFAM: sodium/calcium exchanger membrane region; KEGG: rlt:Rleg2_2731 sodium/calcium exchanger membrane region.
  
    0.429
Slit_0115
KEGG: mei:Msip34_2803 glutamate synthase (ferredoxin); PFAM: glutamate synthase; ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein.
  
  
 0.424
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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