STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slit_0745PFAM: Lytic transglycosylase catalytic; KEGG: mei:Msip34_2278 lytic transglycosylase catalytic. (213 aa)    
Predicted Functional Partners:
proS
prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...]
       0.806
Slit_0007
KEGG: mfa:Mfla_0188 peptidoglycan-binding LysM; PFAM: Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding LysM.
  
     0.688
Slit_0110
PFAM: Pilus assembly protein PilO; KEGG: neu:NE2314 putative fimbrial type-4 assembly membrane transmembrane protein.
  
     0.668
Slit_0109
PFAM: Fimbrial assembly family protein; KEGG: tbd:Tbd_0203 type IV pilus assembly protein PilN.
  
     0.660
Slit_0111
PFAM: Pilus assembly protein PilP; KEGG: tbd:Tbd_0205 type IV pilus assembly protein PilP.
  
     0.636
rppH
NUDIX hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily.
   
   0.626
Slit_0112
Type IV pilus secretin PilQ; KEGG: azo:azo3646 type 4 fimbrial biogenesis protein; TIGRFAM: type IV pilus secretin PilQ; PFAM: type II and III secretion system protein; NolW domain protein; Secretin/TonB short domain.
  
     0.614
Slit_0108
TIGRFAM: type IV pilus assembly protein PilM; KEGG: dar:Daro_0210 type IV pilus assembly protein PilM.
  
     0.609
Slit_2120
KEGG: tbd:Tbd_1918 hypothetical protein; TIGRFAM: FimV N-terminal domain; FimV C-terminal domain; PFAM: Peptidoglycan-binding lysin domain.
  
     0.581
Slit_0618
Flagellar hook-associated 2 domain protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
 
    0.543
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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