Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_0800Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. (153 aa)    
Predicted Functional Partners:
Slit_1965
KEGG: mfa:Mfla_2424 single-strand binding protein; TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n.
  
  
 
0.901
priA
Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.
  
 
 
 0.836
dnaX
DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
    
 
 0.825
Slit_2567
TIGRFAM: DNA polymerase III, alpha subunit; PFAM: DNA polymerase III alpha subunit; nucleic acid binding OB-fold tRNA/helicase-type; PHP domain protein; KEGG: mei:Msip34_1749 DNA polymerase III, alpha subunit; SMART: phosphoesterase PHP domain protein.
   
 
 0.818
Slit_2411
PFAM: DNA polymerase III chi subunit HolC; KEGG: nmu:Nmul_A0745 DNA polymerase III chi subunit, HolC.
    
 
 0.813
rpsF
Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
  
  
 0.803
Slit_0799
PFAM: major facilitator superfamily MFS_1; KEGG: nmu:Nmul_A2228 major facilitator transporter.
       0.793
rpsB
Ribosomal protein S2; KEGG: nmu:Nmul_A0657 30S ribosomal protein S2; TIGRFAM: ribosomal protein S2; PFAM: ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
  
  0.755
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
 0.745
Slit_1856
PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein; Enoyl-CoA hydratase/isomerase; KEGG: nmu:Nmul_A0097 3-hydroxyacyl-CoA dehydrogenase, NAD-binding.
   
 
 0.700
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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