Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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Slit_0805Fe-S cluster assembly protein NifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins. (296 aa)    
Predicted Functional Partners:
Slit_0806
Cysteine desulfurase NifS; Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.
 
 0.999
iscS
Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
 
 0.995
Slit_0804
KEGG: azo:azo0554 HesB/YadR/YfhF family protein; TIGRFAM: iron-sulfur cluster assembly accessory protein; PFAM: HesB/YadR/YfhF-family protein; Belongs to the HesB/IscA family.
 
 0.991
Slit_1838
KEGG: cvi:CV_1068 succinate dehydrogenase iron-sulfur subunit; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
 0.980
Slit_2253
KEGG: dar:Daro_1952 HesB/YadR/YfhF:iron-sulphur cluster assembly protein IscA; TIGRFAM: iron-sulfur cluster assembly protein IscA; iron-sulfur cluster assembly accessory protein; PFAM: HesB/YadR/YfhF-family protein; Belongs to the HesB/IscA family.
  
 0.946
erpA
Iron-sulfur cluster assembly accessory protein; Required for insertion of 4Fe-4S clusters.
  
 0.946
Slit_2005
KEGG: nmu:Nmul_A0892 Dna-J like membrane chaperone protein; PFAM: heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein.
  
 0.939
hscB
Co-chaperone Hsc20; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.
  
 0.939
Slit_2375
PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; ferredoxin; KEGG: mca:MCA2508 oxygenase, putative.
  
 0.923
Slit_0273
PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; ferredoxin; KEGG: tbd:Tbd_2563 CDP-6-deoxy-delta-3,4-glucoseen reductase.
  
 0.921
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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