Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Slit_0822PFAM: protein of unknown function DUF162; KEGG: rfr:Rfer_0200 hypothetical protein. (223 aa)    
Predicted Functional Partners:
Slit_0823
KEGG: rfr:Rfer_0199 iron-sulfur cluster binding protein; TIGRFAM: iron-sulfur cluster binding protein; PFAM: protein of unknown function DUF162; 4Fe-4S ferredoxin iron-sulfur binding domain protein.
 
 
 0.997
Slit_0821
PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: rfr:Rfer_0201 protein of unknown function DUF224, cysteine-rich protein.
 
 
 0.971
Slit_0333
PFAM: FAD linked oxidase domain protein; KEGG: mei:Msip34_2262 FAD linked oxidase domain protein.
  
 
 0.686
Slit_0820
Hypothetical protein; KEGG: Gm3773; predicted gene 3773.
       0.625
Slit_0450
Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+))., Phosphate acetyltransferase; KEGG: azo:azo3211 malic enzyme; PFAM: malic protein NAD-binding; malic protein domain protein; phosphate acetyl/butaryl transferase.
  
  
 0.621
Slit_0303
KEGG: tgr:Tgr7_0836 protein of unknown function DUF224 cysteine-rich region domain protein.
 
 
 0.557
Slit_0825
PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: hch:HCH_05804 glycolate oxidase iron-sulfur subunit.
 
 
 0.553
Slit_0840
PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: azo:azo0062 hypothetical protein.
 
 
 0.541
Slit_2486
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding; Pyruvate/ketoisovalerate oxidoreductase; KEGG: hha:Hhal_0066 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein.
     
 0.477
Slit_1619
PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: tbd:Tbd_1376 heterodisulfide reductase.
  
 
 0.460
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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