Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_0825PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: hch:HCH_05804 glycolate oxidase iron-sulfur subunit. (415 aa)    
Predicted Functional Partners:
Slit_0826
PFAM: FAD linked oxidase domain protein; KEGG: afe:Lferr_1361 glycolate oxidase FAD binding subunit.
 
 0.997
Slit_0827
PFAM: FAD linked oxidase domain protein; KEGG: noc:Noc_0495 D-lactate dehydrogenase (cytochrome).
 
 0.997
Slit_0824
Serine--pyruvate transaminase; KEGG: noc:Noc_2128 aminotransferase, class V; PFAM: aminotransferase class V.
    
  0.976
gph
Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
     
  0.900
Slit_1754
KEGG: app:CAP2UW1_1528 HAD-superfamily hydrolase, subfamily IA, variant 1; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase.
     
  0.900
Slit_0823
KEGG: rfr:Rfer_0199 iron-sulfur cluster binding protein; TIGRFAM: iron-sulfur cluster binding protein; PFAM: protein of unknown function DUF162; 4Fe-4S ferredoxin iron-sulfur binding domain protein.
 
 
 0.649
Slit_1360
PFAM: protein of unknown function DUF336; KEGG: nmu:Nmul_A0738 hypothetical protein.
 
  
 0.566
Slit_0822
PFAM: protein of unknown function DUF162; KEGG: rfr:Rfer_0200 hypothetical protein.
 
 
 0.553
Slit_0828
PFAM: Pirin domain protein; KEGG: ajs:Ajs_1985 pirin domain-containing protein; Belongs to the pirin family.
  
    0.526
Slit_2486
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding; Pyruvate/ketoisovalerate oxidoreductase; KEGG: hha:Hhal_0066 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein.
     
 0.488
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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