Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_0831PFAM: Peptidase S24/S26A/S26B, conserved region; KEGG: dde:Dde_2974 SOS mutagenesis protein UmuD; Belongs to the peptidase S24 family. (159 aa)    
Predicted Functional Partners:
Slit_0830
KEGG: mei:Msip34_1607 DNA-directed DNA polymerase; PFAM: UMUC domain protein DNA-repair protein.
 
 
 0.981
recA
recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.935
Slit_1049
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
   
  
 0.612
Slit_0832
ADP-ribosyl-(dinitrogen reductase) hydrolase; TIGRFAM: ADP-ribosyl-[dinitrogen reductase] hydrolase; KEGG: dar:Daro_1447 ADP-ribosylation/crystallin J1; PFAM: ADP-ribosylation/Crystallin J1.
       0.571
Slit_0833
PFAM: NifQ family protein; KEGG: hha:Hhal_0280 NifQ family protein.
       0.566
Slit_2439
KEGG: lch:Lcho_4294 XRE family transcriptional regulator; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein.
     
 0.478
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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