STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slit_0856Transcriptional regulator, NifA, Fis Family; TIGRFAM: Nif-specific regulatory protein; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; GAF domain protein; KEGG: azo:azo0519 nif-specific regulatory protein; SMART: GAF domain protein; AAA ATPase. (517 aa)    
Predicted Functional Partners:
Slit_0857
PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: nitrogen fixation negative regulator NifL; PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; KEGG: azo:azo0518 nitrogen fixation regulatory protein; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; PAC repeat-containing protein.
 
 
 0.992
Slit_0013
Two component transcriptional regulator, Fis family; KEGG: reh:H16_A3694 response regulator; PFAM: response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver.
 
 
   0.911
Slit_0663
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; GGDEF domain containing protein; PAS fold domain protein; KEGG: dar:Daro_3099 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); SMART: EAL domain protein; GGDEF domain containing protein; PAC repeat-containing protein; PAS domain containing protein.
   
 
 0.872
Slit_0436
RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
   
 0.851
Slit_1299
KEGG: rfr:Rfer_1982 response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: response regulator receiver; SMART: response regulator receiver.
 
 
   0.638
Slit_0811
PFAM: NifZ family protein; KEGG: azo:azo0547 nitrogen fixation protein.
 
   
 0.619
nifW
Nitrogen fixation protein NifW; May protect the nitrogenase Fe-Mo protein from oxidative damage; Belongs to the NifW family.
 
   
 0.600
Slit_0837
KEGG: azo:azo0523 nitrogen fixation protein; TIGRFAM: nitrogenase cofactor biosynthesis protein NifB; PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis protein; Radical SAM domain protein.
 
   
 0.597
Slit_2784
Histidine kinase; KEGG: cyn:Cyan7425_1575 histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein.
  
 
 
 0.564
Slit_0884
KEGG: app:CAP2UW1_4450 nitrogen fixation protein FixT; TIGRFAM: nitrogen fixation protein FixT; PFAM: NifT/FixU family protein.
 
   
 0.551
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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