close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slit_0889KEGG: rfr:Rfer_2293 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region. (202 aa)    
Predicted Functional Partners:
Slit_1545
Diguanylate cyclase with GAF sensor; SMART: GGDEF domain containing protein; GAF domain protein; TIGRFAM: diguanylate cyclase; KEGG: mms:mma_3133 hypothetical protein; PFAM: GGDEF domain containing protein.
 
 
   0.945
Slit_1774
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-4 domain protein; KEGG: aha:AHA_3237 GGDEF domain-containing protein; SMART: GGDEF domain containing protein.
 
 
   0.939
Slit_2225
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver; KEGG: azo:azo2059 REC/GGDEF-domain-containing protein; SMART: GGDEF domain containing protein; response regulator receiver.
 
   
 0.930
Slit_1239
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: aav:Aave_4776 diguanylate cyclase; SMART: GGDEF domain containing protein.
 
 
   0.929
Slit_2624
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: hch:HCH_04724 response regulator; SMART: GGDEF domain containing protein.
 
 
   0.928
Slit_1029
TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; PAS fold domain protein; KEGG: mag:amb1535 response regulator; SMART: GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein.
 
 
 
 0.920
Slit_1163
KEGG: mag:amb1840 response regulator; PFAM: response regulator receiver; SMART: response regulator receiver.
 
    
 0.902
Slit_1314
Diguanylate cyclase; SMART: GGDEF domain containing protein; TIGRFAM: diguanylate cyclase; KEGG: azo:azo3777 GGDEF family protein; PFAM: GGDEF domain containing protein.
 
 
   0.797
Slit_2804
TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; PAS fold domain protein; KEGG: dps:DP2309 hypothetical protein; SMART: GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein.
 
 
 
 0.778
Slit_1232
PFAM: metal-dependent phosphohydrolase HD sub domain; KEGG: maq:Maqu_0258 metal dependent phosphohydrolase.
  
     0.774
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.