STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
Slit_0936Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; histidine kinase HAMP region domain protein; GGDEF domain containing protein; PAS fold-3 domain protein; KEGG: mei:Msip34_1597 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); SMART: EAL domain protein; GGDEF domain containing protein; PAC repeat-containing protein; histidine kinase HAMP region domain protein. (830 aa)    
Predicted Functional Partners:
Slit_1299
KEGG: rfr:Rfer_1982 response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: response regulator receiver; SMART: response regulator receiver.
 
 
 0.879
Slit_1160
KEGG: mgm:Mmc1_3164 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein.
 
 
 0.844
Slit_1163
KEGG: mag:amb1840 response regulator; PFAM: response regulator receiver; SMART: response regulator receiver.
 
 
 0.807
Slit_0937
KEGG: aba:Acid345_0937 hypothetical protein.
       0.778
Slit_1455
Diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; GGDEF domain containing protein; extracellular solute-binding protein family 3; PAS fold-4 domain protein; GAF domain protein; KEGG: rfr:Rfer_0458 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); SMART: EAL domain protein; GGDEF domain containing protein; extracellular solute-binding protein family 3; PAS domain containing protein; GAF domain protein; PAC repeat-containing protein.
 
 
0.718
Slit_0938
PFAM: TonB-dependent receptor plug; TonB-dependent receptor; KEGG: app:CAP2UW1_2789 TonB-dependent receptor.
       0.714
Slit_2160
TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; CHASE domain protein; MASE1 domain protein; PAS fold domain protein; PAS fold-3 domain protein; KEGG: tgr:Tgr7_1851 diguanylate cyclase/phosphodiesterase with PAS/PAC and CHASE sensor(s); SMART: GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein.
 
 
0.709
Slit_2024
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; PAS fold domain protein; PAS fold-4 domain protein; GGDEF domain containing protein; KEGG: rfr:Rfer_3395 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein.
 
 
0.704
Slit_2226
TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; histidine kinase HAMP region domain protein; PAS fold domain protein; PAS fold-4 domain protein; KEGG: dar:Daro_4048 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); SMART: GGDEF domain containing protein; histidine kinase HAMP region domain protein; PAS domain containing protein; PAC repeat-containing protein.
 
 
0.687
Slit_1666
Diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein; histidine kinase HAMP region domain protein; GAF domain protein; TIGRFAM: diguanylate cyclase; PAS sensor protein; KEGG: mfa:Mfla_2628 diguanylate cyclase/phosphodiesterase; PFAM: EAL domain protein; PAS fold-4 domain protein; histidine kinase HAMP region domain protein; GGDEF domain containing protein; GAF domain protein.
 
 
 
0.669
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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