Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_0938PFAM: TonB-dependent receptor plug; TonB-dependent receptor; KEGG: app:CAP2UW1_2789 TonB-dependent receptor. (715 aa)    
Predicted Functional Partners:
Slit_0937
KEGG: aba:Acid345_0937 hypothetical protein.
 
     0.942
Slit_0936
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; histidine kinase HAMP region domain protein; GGDEF domain containing protein; PAS fold-3 domain protein; KEGG: mei:Msip34_1597 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); SMART: EAL domain protein; GGDEF domain containing protein; PAC repeat-containing protein; histidine kinase HAMP region domain protein.
       0.714
Slit_0940
KEGG: dar:Daro_3160 hypothetical protein.
   
   0.619
Slit_0941
KEGG: mfa:Mfla_0206 hypothetical protein.
   
   0.619
Slit_0507
TIGRFAM: TonB family protein; KEGG: neu:NE1626 putative TonB protein.
 
 
 0.589
Slit_1388
TonB family protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
 
 0.547
Slit_0939
PFAM: Fmu (Sun) domain protein; KEGG: neu:NE0085 SAM (and some other nucleotide) binding motif; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
       0.511
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
       0.511
purM
TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; KEGG: nmn:NMCC_1133 phosphoribosylaminoimidazole synthetase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein.
       0.511
Slit_0519
TIGRFAM: protein TolA; KEGG: neu:NE0217 hypothetical protein.
  
 
 0.484
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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