STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slit_0945KEGG: tgr:Tgr7_1417 outer membrane protein domain-containing protein. (202 aa)    
Predicted Functional Partners:
Slit_1384
PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: dar:Daro_2953 TonB-dependent receptor.
    
 
 0.721
Slit_0946
KEGG: nmu:Nmul_A2615 HAD family hydrolase; TIGRFAM: HAD-superfamily subfamily IB hydrolase, TIGR01490; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase.
       0.566
Slit_0944
KEGG: mfa:Mfla_0204 regulatory inactivation of DnaA Hda protein; TIGRFAM: DnaA regulatory inactivator Hda; PFAM: Chromosomal replication initiator DnaA; Belongs to the DnaA family.
     
 0.535
Slit_0494
KEGG: nmu:Nmul_A1896 general secretion pathway protein I; TIGRFAM: general secretion pathway protein I; PFAM: type II secretion system protein I/J.
  
     0.492
pcnB
poly(A) polymerase; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
       0.410
Slit_0948
TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; KEGG: neu:NE0070 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK.
       0.410
Slit_0949
PFAM: deoxynucleoside kinase; KEGG: nmu:Nmul_A0880 deoxynucleoside kinase.
       0.410
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
       0.410
panC
Pantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
       0.410
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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