STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Slit_0977Quinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (365 aa)    
Predicted Functional Partners:
Slit_1273
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
 0.999
Slit_2204
TIGRFAM: nicotinate-nucleotide pyrophosphorylase; KEGG: mei:Msip34_0611 nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family.
 
 0.999
Slit_0976
PFAM: NUDIX hydrolase; KEGG: neu:NE2253 dATP pyrophosphohydrolase.
     
 0.798
aspS
aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
       0.793
Slit_0974
PFAM: guanine-specific ribonuclease N1 and T1; KEGG: dar:Daro_0633 guanine-specific ribonuclease N1 and T1.
       0.773
Slit_0975
KEGG: azo:azo3242 hypothetical protein.
       0.773
Slit_0971
TIGRFAM: regulatory protein, FmdB family; PFAM: Putative regulatory protein FmdB; KEGG: azo:azo3237 hypothetical protein; SMART: Putative regulatory protein FmdB.
       0.679
Slit_0972
PFAM: protein of unknown function DUF502; KEGG: tbd:Tbd_0441 transmembrane protein.
       0.679
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
    0.677
clsB
Phospholipase D/Transphosphatidylase; Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
       0.666
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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