STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cbbLRibulose-bisphosphate carboxylase; RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site; Belongs to the RuBisCO large chain family. Type I subfamily. (473 aa)    
Predicted Functional Partners:
Slit_0986
KEGG: tbd:Tbd_2623 ribulose 1,5-bisphosphate carboxylase small subunit; PFAM: ribulose bisphosphate carboxylase small chain.
 
 0.998
Slit_2846
KEGG: tbd:Tbd_2447 phosphoribulokinase; PFAM: phosphoribulokinase/uridine kinase.
 
 
 0.978
Slit_0022
KEGG: tbd:Tbd_2638 ribulose bisphosphate carboxylase; PFAM: ribulose bisphosphate carboxylase large chain; Ribulose bisphosphate carboxylase, large subunit-like; Belongs to the RuBisCO large chain family.
  
  
 
0.918
pgk
KEGG: mei:Msip34_0485 phosphoglycerate kinase; PFAM: phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
    
 0.905
gph
Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
    
  0.903
Slit_1754
KEGG: app:CAP2UW1_1528 HAD-superfamily hydrolase, subfamily IA, variant 1; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase.
     
  0.900
Slit_0984
Transcriptional regulator, LysR family; PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: cyn:Cyan7425_3855 transcriptional regulator, LysR family.
 
   
 0.784
Slit_0988
KEGG: rme:Rmet_1498 von Willebrand factor, type A; PFAM: von Willebrand factor type A; SMART: von Willebrand factor type A.
 
   
 0.745
Slit_2742
KEGG: cyb:CYB_0748 HAD family hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase.
 
   
 0.687
acsA
acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
      
 0.635
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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