Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Slit_0997KEGG: lch:Lcho_3118 arsenical-resistance protein; TIGRFAM: arsenical-resistance protein; PFAM: Bile acid:sodium symporter. (343 aa)    
Predicted Functional Partners:
Slit_0996
KEGG: rhi:NGR_b21810 arsenate reductase; PFAM: Protein-tyrosine phosphatase, low molecular weight; SMART: Protein-tyrosine phosphatase, low molecular weight.
  
 0.994
Slit_0995
SMART: regulatory protein ArsR; KEGG: mei:Msip34_1149 transcriptional regulator, ArsR family.
 
  
 0.900
Slit_0998
RNA polymerase, sigma-24 subunit, ECF subfamily; KEGG: rfr:Rfer_3639 sigma-24 (FecI-like); TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; Belongs to the sigma-70 factor family. ECF subfamily.
     
 0.724
Slit_0999
PFAM: permease; KEGG: psa:PST_0233 permease.
  
  
 0.542
Slit_0866
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: lch:Lcho_1553 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein.
     
 0.515
Slit_2768
PFAM: cytochrome c biogenesis protein transmembrane region; alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; KEGG: oca:OCAR_6268 cytochrome c biogenesis protein, transmembrane region.
     
 0.492
Slit_1760
KEGG: cja:CJA_1783 protein-tyrosine-phosphatase; PFAM: Protein-tyrosine phosphatase, low molecular weight; SMART: Protein-tyrosine phosphatase, low molecular weight.
  
  
 0.473
Slit_1000
Hypothetical protein; KEGG: rha:RHA1_ro01495 alanine dehydrogenase.
       0.455
Slit_1002
KEGG: psa:PST_0232 thiol-disulfide isomerase and thioredoxins family protein.
     
 0.438
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
Server load: low (20%) [HD]