Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Slit_1016KEGG: tbd:Tbd_1242 hypothetical protein. (253 aa)    
Predicted Functional Partners:
Slit_1017
KEGG: aeh:Mlg_2566 DJ-1 family protein; TIGRFAM: DJ-1 family protein; PFAM: ThiJ/PfpI domain protein.
       0.773
Slit_1018
KEGG: cli:Clim_0823 phosphoesterase PA-phosphatase related; PFAM: phosphoesterase PA-phosphatase related; SMART: phosphoesterase PA-phosphatase related.
       0.773
Slit_1019
PFAM: protein of unknown function DUF520; KEGG: tbd:Tbd_1846 putative nucleotide-binding protein; Belongs to the UPF0234 family.
       0.682
ycgR
YcgR family protein; Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility.
  
     0.681
Slit_0619
PFAM: flagellar protein FlaG protein; KEGG: tbd:Tbd_1591 putative flagellar protein FlaG.
 
     0.668
ycgR-2
Type IV pilus assembly PilZ; Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility.
  
     0.666
Slit_2611
PFAM: protein of unknown function DUF1058; KEGG: eba:ebA1059 of unknown function.
  
     0.632
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
  
 
 0.603
Slit_0939
PFAM: Fmu (Sun) domain protein; KEGG: neu:NE0085 SAM (and some other nucleotide) binding motif; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
  
 
 0.554
Slit_1376
Putative signal transduction protein; PFAM: Metal-dependent hydrolase HDOD; KEGG: mei:Msip34_2001 metal-dependent hydrolase HDOD.
  
     0.553
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
Server load: low (8%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.